患有COPD的成年人中的全球疹子负担:系统性审查和元分析
Alvaro A Cruz1, Kevin J Mortimer2,3,4, Ingrid T Sepúlveda-Pachón5
1ProAR Foundation and Federal University of Bahia, Salvador, Brazil.
概括
患有慢性阻塞性肺病 (COPD) 的个人面临更高的疹感染风险. 建议接种疫苗以减轻这种风险并减少医疗负担.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 慢性阻塞性肺病 (COPD) 增加了对感染的易感性,包括疹.
- 带状疹可能导致COPD患者的显著发病率和死亡率.
- 本综述综合了关于疹在COPD患者群体中的负担的证据.
研究的目的:
- 系统地审查和分析COPD成年人疹病的全球负担.
- 评估COPD患者中疹菌的发病率,风险,并发症和医疗影响.
主要方法:
- 进行了全球系统文献综述和元分析.
- 从2003年到2024年,搜索了MEDLINE和Embase数据库.
- 包括有关COPD成年人疹发病率,风险,并发症和医疗资源利用情况的研究.
主要成果:
- 在患有COPD的成年人 (≥18岁) 中,疹的综合发病率为每1000人年10.98.
- 患有慢性肺炎的患者患上疹的风险高出1.49倍,而服用皮质类固醇的人 (1.86倍) 的风险更高.
- 带状疹与医疗保健成本增加,资源使用和潜在的COPD恶化有关.
结论:
- 患有COPD的成年人患有黄疹及其并发症的风险较高.
- 在COPD患者中使用皮质类固醇进一步增加了疹风险.
- 疹疫苗接种对COPD患者有效,可以减少疾病负担和医疗保健成本.
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