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scLong:一个十亿参数基础模型,用于捕捉单细胞转录组学中的远程基因上下文

Ding Bai1, Shentong Mo1, Ruiyi Zhang2

  • 1Mohamed bin Zayed University of Artificial Intelligence, Masdar City, Abu Dhabi, UAE.

Nature communications
|February 4, 2026
PubMed
概括

新的基础模型scLong分析了单细胞RNA测序数据中的所有基因,包括低表达的基因. 它整合了基因知识,以改善基因调节和药物反应的预测.

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