相关实验视频

Updated: Feb 6, 2026

Subtype-selective Electroporation of Cortical Interneurons
06:42

Subtype-selective Electroporation of Cortical Interneurons

Published on: August 18, 2014

9.2K

选择性Lis1无活化会扰乱皮质体静止素内部神经元的迁移和定位

A Pombero1, R García-López1, E Geijo-Barrientos1

  • 1Instituto de Neurociencias, UMH-CSIC, Campus de San Juan, E- 03550- Alicante, Alicante, E-03550, Spain.

Scientific reports
|February 4, 2026
PubMed
概括

索马托斯坦丁阳性 (SST+) 内神经元中的Lis1基因缺失会损害它们的迁移,并减少它们在皮质中的数量. 这表明Lis1对于SST+内部神经元发育和皮质组织至关重要.

关键词:
在Cingulate皮层.列表 列表 列表索马托斯塔丁是一种体质的药物.

更多相关视频

Differentiation of Mouse Embryonic Stem Cells into Cortical Interneuron Precursors10:24

Differentiation of Mouse Embryonic Stem Cells into Cortical Interneuron Precursors

Published on: December 3, 2017

10.9K
Transplantation of Chemogenetically Engineered Cortical Interneuron Progenitors into Early Postnatal Mouse Brains06:09

Transplantation of Chemogenetically Engineered Cortical Interneuron Progenitors into Early Postnatal Mouse Brains

Published on: August 26, 2019

6.4K

相关概念视频

X-Inactivation01:58

X-Inactivation

The human X chromosome contains over ten times the number of genes as in the Y chromosome. Since males have only one X chromosome, and females have two, one might expect females to produce twice as many of the proteins, with undesirable results.
42.3K
Position-effect Variegation02:32

Position-effect Variegation

In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
7.1K
Positive Regulator Molecules01:45

Positive Regulator Molecules

To consistently produce healthy cells, the cell cycle—the process that generates daughter cells—must be precisely regulated.
136.4K
Activation and Inactivation of G Proteins01:22

Activation and Inactivation of G Proteins

Heterotrimeric G proteins are guanine nucleotide-binding proteins. As the name suggests, heterotrimeric G proteins are composed of three subunits: alpha, beta, and gamma. They remain GDP-bound or GTP-bound inside the cells and switch between inactive/active states. The Gα subunit possesses the nucleotide-binding pocket that binds guanine nucleotides and switches between GDP or GTP-bound states. In contrast, the Gꞵ and Gγ subunits are always bound together with high...
11.5K
Migration00:53

Migration

Migration is long-range, seasonal movement from one region or habitat to another. This common strategy, carried out by many different organisms around the world, is an adaptive response that typically corresponds to changes in an organism’s environment, like resource availability or climate. Migrations can involve huge groups of thousands of animals as well as single individuals traveling alone and can range from thousands of kilometers to just a few hundred meters.
8.9K
What is Natural Selection?01:32

What is Natural Selection?

Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
129.5K