开发和验证一种工具,以评估巴西患者对华法林治疗 (TAAW) 的坚持
Carolina Barbosa Ferreira1, Mayara Sousa Vianna2, Adriana Silvina Pagano3
1Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
British journal of clinical pharmacology
|February 4, 2026
概括
一个新的工具,华法林治疗坚持评估工具 (TAAW),有效地测量患者对华法林的坚持. 这种经过验证的工具有助于识别更好的治疗结果的坚持模式.
科学领域:
- 药理学和治疗学 药理学和治疗学
- 临床药房 临床药房
- 患者坚持的研究研究.
背景情况:
- 华法林治疗需要严格遵守有效性和安全性.
- 评估对华法林的坚持是复杂的,涉及多个与患者相关的因素.
- 需要一个经过验证的工具来全面评估不同患者群体的华法林坚持.
研究的目的:
- 开发和验证一个多维工具来评估对华法林治疗的坚持.
- 该工具旨在捕捉患者遵守的各种方面,包括药物摄入,自我护理和健康监测.
- 确保该工具在巴西患者中的可靠性和有效性.
主要方法:
- 基于概念地图,开发用于评估对华法林治疗的坚持 (TAAW) 的工具.
- 通过专家评估和语义分析进行代改进,共30名参与者.
- 心理测量验证包括探索性因子分析,内部一致性,测试复试可靠性和假设测试.
主要成果:
- 最终的TAAW包括21个项目,跨越三个维度:华法林摄入量,自我护理和健康监测.
- 该工具表现出了出色的内部一致性 (克朗巴赫α=0.98) 和高的测试复试可靠性 (ICC=0.96).
- 与治疗范围内的时间有很强的相关性 (斯皮尔曼的rho=0.91) 证实了该工具的有效性.
结论:
- 经过验证的TAAW是评估华法林治疗坚持性的强有力的工具.
- 它提供了一种全面的方法来识别临床和研究环境中的坚持模式.
- 该TAAW促进有针对性的干预措施,以优化抗凝结结果.
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