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Updated: Feb 6, 2026

Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells
05:02

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乳腺癌转移中的ISG15驱动的免疫调节和瘤进展:从单细胞和空间转录组学的见解

Hua Shao1, Hanlu Tang2, Huiying Lin2

  • 1Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110004, China.

BMC medicine
|February 4, 2026
PubMed
概括

乳腺癌干细胞中的干扰素刺激基因15 (ISG15) 通过促进M2巨分离和抑制T细胞反应,驱动淋巴结转移. 沉默ISG15抑制瘤生长和转移,确定ISG15作为潜在的治疗标.

关键词:
乳腺癌 乳腺癌 乳腺癌癌症干细胞是癌症干细胞.细胞细胞的通信.干扰素刺激基因15 干扰素刺激基因单细胞转录基因组测序

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