MPNST:PDOX使

Sara Ortega-Bertran1,2,3, Juana Fernández-Rodríguez1,2,4,5, Miriam Magallón-Lorenz6

  • 1Hereditary Cancer Program, Catalan Institute of Oncology (ICO-IDIBELL), Hospitalet de Llobregat, Barcelona, Spain.

PubMed
概括

针对恶性外围神经膜瘤 (MPNSTs) 的个性化药物集成了基因组分析与患者衍生异种移植 (PDOX) 模型. 结合MEK和odomain抑制剂的联合疗法在治疗MPNST方面显示出有前途.

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