假肢遮器的瘤结果与腔鼻恶性瘤的腔切除术后的自由片重建相比
Young-Ha Lee1, Sung Seok Ryu1, Kyung Won Kwon1
1Department of Otorhinolaryngology-Head and Neck surgery, University of Ulsan College of Medicine, Asan Medical Center.
Clinical and experimental otorhinolaryngology
|February 4, 2026
概括
阻塞器和自由重建为上鼻癌患者提供了类似的生存结果. 实现明显的切除边缘和适当的辅助治疗是关键的预后因素,而不是重建方法本身.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 头部和部手术 头部和部手术
背景情况:
- 大鼻恶性瘤需要手术切除 (大切除术).
- 像阻塞器和自由这样的重建方法具有不同的术后可见性,影响癌症监测.
- 将这些重建方法进行比较对于优化患者的治疗结果至关重要.
研究的目的:
- 为了比较临床病理学和生存结果,在腔鼻瘤的口切除术后,在口切除术和自由口重建之间.
- 在整体队列和状细胞癌 (SCC) 亚组中评估整体生存率 (OS) 和无病生存率 (DFS).
主要方法:
- 进行大切除术的61名患者 (2002-2021) 的回顾性审查.
- 对临床病理特征,切除边缘状态,复发模式和生存 (OS和DFS) 的分析.
- 使用卡普兰-梅尔和多变量考克斯模型,考虑重建方法,阶段,边缘和辅助疗法.
主要成果:
- 阻塞器组的患者年龄较大,更有可能接受全额大切除术.
- 在阻塞器和自由重建组之间没有观察到OS或DFS的显著差异.
- 接近/积极的边际和缺乏辅助治疗与较差的生存率有关;重建方法不是一个重要的因素.
结论:
- 阻塞器和自由重建在上鼻癌中产生了相似的存活率.
- 切除边缘状态和术后辅助疗法是关键的预后指标.
- 个人重建决策,足够的边际和适当的辅助治疗是必不可少的.
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