治疗ADHD的人群中的并发症和共用药:丹麦全国性的研究
Maria Vestergaard1, Rikke Faergemann Hansen2, Per Hove Thomsen3
1Signum Life Science, Real World Evidence, Lersø Parkallé 101, Copenhagen K, 2100 , Denmark. mve@signumlifescience.com.
BMC psychiatry
|February 4, 2026
概括
接受治疗的注意力缺陷多动性障碍 (ADHD) 患者的体质和精神病并发症率明显较高,并使用更多的精神病药物. 这突出了复杂的疾病负担,需要改进的管理策略.
科学领域:
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 注意缺陷多动症 (ADHD) 是一种神经发育障碍,对公共健康有重大影响.
- 伴随性疾病和多药性是ADHD管理中的常见问题.
- 了解治疗多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性多动性.
研究的目的:
- 在接受ADHD医疗治疗的个体中调查体质和精神伴随性疾病的患病率.
- 评估在治疗多动症多动症患者中使用精神科药物的情况.
- 将这些比率与来自一般人口的匹配对照组进行比较.
主要方法:
- 一项全国性的病例控制研究,利用丹麦卫生数据管理局2013-2023年的记录.
- 包括98,398名患有ADHD药物处方的个人和1,082,378名匹配的对照人群 (1:10).
- 使用条件后勤回归模型来估计关联.
主要成果:
- 患有多动症的个体具有更高的并发症率 (46.7%与23.3%) 和精神病药物使用率 (32.7%与7.2%).
- 在所有年龄组中,ADHD治疗与体质和精神病并发症的几率增加有关.
- 与非ADHD对照人群相比,年龄在7-29岁的女性出现并发症的几率特别高.
结论:
- 治疗ADHD与伴随疾病和精神病学药物治疗的患病率显著增加有关.
- 这些发现强调了治疗多动症多动症患者的复杂疾病负担,特别是在年轻女性中.
- 加强疾病管理策略是有必要的,以减轻并发症和改善生活质量.
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