印度比哈尔州一个被囚禁的亚洲大象 (Elephas maximus) 患狂犬病:第一例确诊病例与前和死后诊断
Ramesh Tiwary1, Pallav Shekhar2, Pankaj Kumar3
1Department of Veterinary Surgery and Radiology, Bihar Veterinary College, Bihar Animal Sciences University, Patna, India.
Zoonoses and public health
|February 5, 2026
概括
这项研究报告了在印度被囚禁的亚洲大象中首次确诊的狂犬病病例. 诊断证实使用前验尸和后验尸测试,突出动物传播疾病的风险.
科学领域:
- 兽医神经学 兽医神经学
- 动物传播疾病 动物传播疾病
- 野生动物保护 野生动物保护
背景情况:
- 狂犬病是一种致命的动物性脑炎,在大象中很少有报道.
- 作为大型哺乳动物,大象可能容易感染动物传播疾病.
- 了解大象的狂犬病传播对公共卫生至关重要.
研究的目的:
- 为了记录印度比哈尔邦被囚禁的亚洲大象中第一个确诊的狂犬病病例.
- 使用前死亡和死后诊断技术来确认狂犬病.
- 讨论这一发现对野生动物保护和公共卫生战略的影响.
主要方法:
- 一个8岁的雌性大象出现了急性神经症状.
- 死前诊断包括在角膜涂抹和唾液上进行光抗体测试 (FAT).
- 尸检后的确认包括在尸检后对脑组织进行直接光抗体 (DFA) 测试.
主要成果:
- 在角膜涂抹中通过FAT检测到狂犬病抗原.
- DFA测试证实小脑和脑干组织中的狂犬病抗原.
- 大象在发病后的第六天死亡;没有明显的咬伤史.
结论:
- 这一案例证实了亚洲大象在囚禁中的狂犬病,这是一个罕见的事件.
- 对所有暴露人员进行了即时的暴露后预防.
- 这一发现强调了对大型动物群的动物传染病需要保持警,并为保护工作提供了信息.
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