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Updated: Feb 6, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

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通过全基因组测序识别的自体主导或X关联的de novo变异中父亲年龄的影响

Ella Beraldo1, Shelin Adam2, Colleen Guimond2

  • 1BC Children's Hospital Research Institute, Vancouver, BC, V5Z 4H4, Canada; Genome Science and Technology, University of British Columbia, Vancouver, BC, V5Z 4S6, Canada.

HGG advances
|February 5, 2026
PubMed
概括

年长的父亲有更高的机会将新的遗传突变传给他们的孩子,增加零星自体主导性疾病的风险. 这项研究分析了家庭中的遗传变异,证实了父亲年龄对新突变的影响.

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