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Updated: Feb 6, 2026

05:02
Listeria monocytogenes Infection of the Brain
Published on: October 2, 2018
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李斯特菌单细胞菌的持久性:一个整合性的叙事审查
Raúl A Poutou-Piñales1, Sandra M Rincón-Gamboa1,2, Ana K Carrascal-Camacho2
1Laboratorio de Biotecnología Molecular, Grupo de Biotecnología Ambiental e Industrial (GBAI), Departamento de Microbiología, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia.
Frontiers in microbiology
|February 5, 2026
概括
李斯特菌单细胞菌的持久性是一个由遗传和环境因素驱动的食品安全问题. 了解这些决定因素对于制定有效的,跨学科的农业和工业控制策略至关重要.
科学领域:
- 食品安全 食品安全
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- *Listeria monocytogenes由于在各种环境中持久存在,因此对公共卫生构成重大风险.
- * 它的生存能力归因于遗传,生理和生态适应能力.
- *这种适应性使食品安全,农业和工业的控制措施复杂化.
研究的目的:
- * 审查和综合2000-2025年科学文献的因素,使得Listeria monocytogenes的持久性.
- * 整合临床,农业和工业方面对这一现象的看法.
- * 确定维持长期生存的关键决定因素.
主要方法:
- *对科学出版物的探索性审查.
- *综合来自临床,农业和工业领域的信息.
- *对遗传,分子和环境因素的分析.
主要成果:
- * 特定的克隆复合体 (CC1,CC2,CC4,CC6,CC9,CC31,CC87,CC121,CC321) 与持久性L.单细胞原体有关.
- *分子机制包括赋予对消毒剂和金属耐受性的基因 (例如,qacH,bcrABC,cadAC,mdrL,SSI-1,SSI-2).
- * 截断的inlA变种有利于食物殖民,而胆汁和抗菌素耐药性则促进侵入性感染. 农业系统和加工厂的生物膜有助于储存.
结论:
- *Listeria monocytogenes的持久性是由于遗传,生理和环境因素的复杂相互作用造成的.
- * 农业系统和食品加工环境充当关键储存库.
- * 综合,跨学科的控制策略对于减轻其对食物链的影响至关重要.
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