视觉症状与光盘德鲁森现象型在一组患者中的相关性
Marius B Maartensson1, Steffen Hamann1,2,3
1Department of Ophthalmology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Neuro-ophthalmology (Aeolus Press)
|February 5, 2026
概括
视盘干燥 (ODD) 患者报告类似的视觉症状,无论干燥的位置. 然而,表面的ODD与较大的视觉功能下降相关,尽管患者可能不会感知到这些变化.
科学领域:
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
- 医疗成像医学成像
背景情况:
- 视盘干燥 (ODD) 是一种缓慢进展的视神经病变,症状不清楚.
- 了解ODD,视觉功能和患者报告的症状之间的关系对于管理这种情况至关重要.
研究的目的:
- 研究ODD患者视觉症状,视神经头部解剖学和视觉功能之间的相关性.
- 为了比较表面与深层ODD患者之间的视觉功能和症状.
主要方法:
- 包括118名经过CT验证的ODD患者.
- 参与者填写了视觉功能问卷 (VFQ-25+),OCT扫描和自动周边测量.
- 分析了数据,比较表面与深层ODD和单个眼睛.
主要成果:
- 表面和深层ODD组之间报告的症状 (例如,短暂的视力障碍,眼睛盲) 或VFQ-25+分数没有显著差异.
- 表面ODD的眼睛显示出明显减少的黄斑体积和视网膜神经纤维层厚度.
- 表面的ODD眼睛与深层ODD眼睛相比,周边平均偏差和ODD大小之间的相关性更强.
结论:
- 表面的ODD与更明显的视觉功能下降有关,但症状报告在ODD位置之间是一致的.
- 类似的VFQ-25+得分表明,患者可能无法轻易感知与ODD相关的解剖和功能变化.
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