Guangzong Chen1, Mingui Sun1,2,3, Zhi-Hong Mao1,3

  • 1Department of Electrical and Computer Engineering, University of Pittsburgh, Pittsburgh, PA 15260, USA.

IEEE access : practical innovations, open solutions
|February 5, 2026
PubMed
概括

简化的生成对抗网络 (GAN) 可以实现高质量的图像对图像翻译,而不会造成复杂的损失. 这项研究表明,基本的GAN是足够的,提供了一个更有效和可解释的框架.

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Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
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Translation01:31

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Translation01:31

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Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
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Protein Networks02:26

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Initiation of Translation02:33

Initiation of Translation

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Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
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