不同运动模式干预措施在改善结性脊柱炎患者的疾病活动中的有效性:一个网络和剂量依赖的元分析
Guancheng Ye1, Luyuan Gao1, Chunping Liu1
1Department of Rheumatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Frontiers in physiology
|February 5, 2026
概括
催眠疗法模拟和联合有氧运动显著改善结性脊髓炎 (AS) 症状和胸部膨胀. 个性化的运动处方是管理AS疾病活动和功能的关键.
科学领域:
- 类风湿病学 类风湿病学
- 物理疗法物理治疗
- 运动科学 运动科学
背景情况:
- 化脊柱炎 (AS) 是一种慢性炎症状况,影响身体功能和生活质量.
- 标准治疗包括NSAID和生物药物,但运动对于运动至关重要.
- 焦虑和抑郁等心理负担在AS患者中很常见.
研究的目的:
- 为了比较12项运动干预措施对AS疾病活动和胸部膨胀 (CE) 的影响.
- 进行网络元分析 (NMA) 和剂量反应元分析.
- 为了探索个性化运动处方的剂量依赖效应.
主要方法:
- 根据PRISMA指南,在RCT的系统文献搜索直到2024年12月31日.
- 包括的研究涉及成年人ACR/EULAR诊断AS,比较运动对照组.
- 评估的结果包括BASFI,BASDAI,BASMI和CE;进行了NMA和剂量反应分析.
主要成果:
- 分析了32个RCT,其中有1757名参与者.
- 催眠疗法模拟 (HS) 在减少BASFI方面最有效.
- 有氧运动 (AE) + Pilates在改善BASDAI和BASMI方面表现出色;AE + 伸展运动 (SE) + 监督最好的增强CE.
结论:
- 具体的运动干预措施,如HS,AE + Pilates和AE + SE + 监督显著改善AS疾病活动和CE.
- 非线性剂量反应关系凸显了个性化运动处方的必要性.
- 这些发现提供了基于证据的指导,用于将练习纳入AS管理.
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