怀孕期间急性呼吸困扰综合征 (ARDS) 的体外膜氧化 (ECMO):系统性审查
Islam Kourampi1, Eleni Xourgia2, Aristomenis Exadaktylos3
1Department of Emergency Medicine, University Hospital of Bern (Inselspital), Bern, CHE.
Cureus
|February 5, 2026
概括
身体外膜氧化 (ECMO) 可以在患有严重急性呼吸困扰综合征 (ARDS) 的孕妇中挽救生命. 然而,有限的证据和研究质量需要进一步的研究以实现最佳使用.
科学领域:
- 关键护理医学 关键护理医学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 新生儿科学 新生儿科学
背景情况:
- 孕期急性呼吸窘迫综合征 (ARDS) 是一种罕见但危急的疾病.
- 身体外膜氧化 (ECMO) 是孕妇严重ARDS的潜在救援疗法,但证据有限.
研究的目的:
- 系统地审查与怀孕期间ARDSECMO相关的孕产妇和新生儿结局.
- 描述并发症,并评估现有的ECMO研究在怀孕期间ARDS的质量.
主要方法:
- 在MEDLINE,Embase和Cochrane数据库中进行了全面的搜索.
- 包括观察性研究和病例系列报告ECMO在怀孕期间或产后使用ARDS.
- 使用纽卡斯尔-太华尺度和JBI检查清单来评估偏差风险.
主要成果:
- 分析了13项 (2011-2024) 涉及主要有毒 (VV) ECMO的研究.
- 孕产妇的存活率各不相同 (33%-100%),最近的研究显示>80%的存活率.
- 主要并发症包括出血,血栓栓塞,感染和急性损伤;胎儿的结果取决于妊娠年龄.
结论:
- 对于耐火性ARDS的孕妇/产后患者来说,ECMO可以挽救生命.
- 目前的证据受到观测设计,小样本大小和异质性的限制.
- 需要标准化数据收集和前性研究来优化ECMO在这个人群中的使用.
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