艾米奥达龙诱导的肺毒性呈现为单侧纤维化:一个病例报告
Laxman Wagle1, Anuj Timshina1, Sishir Poudel2
1Internal Medicine, Ascension Saint Agnes Hospital, Baltimore, USA.
Cureus
|February 5, 2026
概括
一个罕见的阿米奥达龙诱导的肺毒性病例 (APT),呈现为单边肺纤维化. 早期药物戒断和治疗改善了患者的病情.
科学领域:
- 肺部病理学 肺部病理学
- 心脏病学 心脏病学
- 毒理学 毒理学 毒理学
背景情况:
- 阿米奥达龙诱导的肺毒性 (APT) 是一种严重的并发症,通常是双边间歇性肺病.
- 非典型的APT表现可能会挑战诊断和治疗.
研究的目的:
- 报告一种罕见的APT病例,呈现为单边肺纤维化.
- 强调识别非典型的APT表现的重要性,以便及时介入.
主要方法:
- 一个86岁的男性长期服用阿米奥达龙的病例报告.
- 诊断工作包括胸部成像,感染/自身免疫/过敏测试和支气管镜检查.
- 治疗包括停用阿米奥达龙和皮质类固醇治疗.
主要成果:
- 胸部成像显示左肺的单边纤维变化和不透明性.
- 广泛的检查排除了肺部疾病的其他原因.
- 患者在停用阿米奥达龙和开始使用皮质类固醇后出现了临床改善.
结论:
- 阿米奥达龙诱导的肺毒性可以表现为单侧肺纤维化,这是一个罕见且具有诊断挑战性的表现.
- 及时识别和停止使用阿米奥达龙对于管理非典型的APT和预防不可逆转的肺损伤至关重要.
相关概念视频
Cystic Fibrosis: Pathogenesis
886
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
886
Data Reporting and Recording
5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
Types of Reports I: Hands-off Report
1.5K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
Cystic Fibrosis: Management
543
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
543
Toxic Reactions: Overview
2.0K
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
2.0K
Types of Reports II: Incident or Occurrence Report
1.3K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.3K


