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Updated: Feb 6, 2026

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在癌症中Shilajit的临床前评估:系统性审查
Sushant S Das1, M Ramkumar1, Harsimranjit Singh1
1Department of Anatomy, All India Institute of Medical Sciences Vijaypur, Jammu, Jammu, IND.
Cureus
|February 5, 2026
概括
在临床前研究中,Shilajit通过诱导癌细胞死亡和抑制瘤生长,显示出抗癌作用. 由于标准化挑战,需要进一步的严格研究来探索其临床潜力.
科学领域:
- 艾尔韦达医学是一种医药.
- 植物化学 植物化学
- 在瘤学瘤学.
背景情况:
- 希拉吉特是一种草药矿物制剂,含有酸和性物质.
- 它的潜在抗癌性质需要对现有证据进行全面审查.
研究的目的:
- 系统地审查和综合关于Shilajit抗癌潜力的临床前和临床证据.
- 分析它的作用机制和转化前景.
主要方法:
- 在PubMed,奥维德发现和谷歌学者的系统文献搜索.
- 包括九项临床前研究 (八项体外,一个体内).
- 对细胞毒性,机制和选择性数据的定性综合.
主要成果:
- 所有研究都报告了Shilajit对各种癌症类型的剂量依赖性细胞毒性.
- 西拉吉特对癌细胞比正常细胞具有选择性.
- 机制包括诱导亡,抑制NF-κB信号传递和细胞循环停止.
结论:
- 在实验模型中,Shilajit显示了多目标的抗癌活动.
- 临床前证据表明,有潜在的化学潜能和器官保护.
- 标准化问题和缺乏临床试验限制了当前的翻译;建议进一步研究.
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