病例报告:将乳腺新辅助化疗后的不同反应与两个病例的细胞内细胞报告进行比较
Danhong Zhan1, Zhikang Li1, Kaiting Yu2
1Laboratory of General Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Frontiers in medicine
|February 5, 2026
概括
细胞内细胞 (CIC) 结构可以预测HER2阳性乳腺癌的治疗反应. 在两个病例中观察到的动态CIC模式表明了个性化新辅助化疗 (NACT) 策略的潜力.
科学领域:
- 在瘤学瘤学.
- 细胞生物学 细胞生物学
背景情况:
- 新辅助化疗 (NACT) 是对HER2阳性乳腺癌的标准.
- 对NACT反应的预测标记是有限的.
- 在各种癌症中观察到细胞内细胞 (CIC) 结构.
研究的目的:
- 研究CIC动态对HER2阳性乳腺癌中NACT的反应中的作用.
- 探索CIC作为治疗结果的潜在预测标记.
主要方法:
- 关于两名 HER2 阳性乳腺癌患者接受 NACT 的病例报告.
- 瘤样本的活检和病理评估.
- 在NACT之前和之后评估CIC频率和复杂性.
主要成果:
- 一名患者对NACT表现出良好的反应,CICs下降.
- 另一位患者的反应有限,持续复杂的CICs.
- 不同的CIC模式与不同的治疗反应相关.
结论:
- 动态CIC模式可能表明瘤对NACT的异质反应.
- CIC结构可以为 HER2 阳性乳腺癌的个性化治疗计划提供见解.
相关概念视频
Data Reporting and Recording
5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
Types of Reports I: Hands-off Report
1.5K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
Types of Reports II: Incident or Occurrence Report
1.3K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.3K
Types of Reports III: Telephone and Verbal Reports
1.0K
Telephone and Verbal Reports in healthcare settings are two communication methods for conveying therapeutic instructions from healthcare providers to nurses or other healthcare staff.
Here's an overview of each type:
Telephone Orders
Here's an overview of each type:
Telephone Orders
1.0K
Reporter Genes
13.3K
Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
13.3K
Introduction to Documentation and Reporting
3.1K
Documentation is the systematic process of formally recording, maintaining, and communicating information.
Nursing documentation records essential information and details regarding a patient's care and treatment in written or electronic form. It is a critical aspect of nursing practice that involves documenting assessments, interventions, outcomes, and other relevant details about a patient's health status.
Documentation maps the patient's health journey by creating a comprehensive...
Nursing documentation records essential information and details regarding a patient's care and treatment in written or electronic form. It is a critical aspect of nursing practice that involves documenting assessments, interventions, outcomes, and other relevant details about a patient's health status.
Documentation maps the patient's health journey by creating a comprehensive...
3.1K


