自然产品作为潜在的资源库,用于控制主要猪肠道病毒
Jialu Zhang1, Yuqian Liu1, Shuying Ren1
1Joint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, 400715, China, southwest.edu.
Transboundary and emerging diseases
|February 5, 2026
概括
天然产品在控制主要的猪肠道病毒 (SEV) 方面表现有前途,如PEDV和PDCoV. 本文重点介绍传统中医药和其他天然化合物作为猪业潜在的抗病毒药物.
科学领域:
- 兽医病毒学 兽医病毒学
- 自然产品化学 自然产品化学
- 猪健康管理 猪健康管理
背景情况:
- 主要的猪肠道病毒 (SEV) 在全球范围内引起猪的重大胃肠道疾病.
- 由于SEV疫情,猪业的经济损失是巨大的.
- 由于特定的抗病毒药物和疫苗的有限可用性,需要采用替代的控制策略.
研究的目的:
- 审查天然产品对主要SEVs的抑制作用.
- 探索传统中医药 (TCM) 和其他天然化合物作为抗病毒剂的潜力.
- 提供研究进展和控制猪肠道病毒感染的新策略的概述.
主要方法:
- 关于天然产品和SEVs的研究的综合文献综述.
- 专注于传统中医 (TCM) 化合物配方,草本提取物,制药单体和天然代谢物.
- 分析天然产品对SEVs施加抗病毒作用的机制.
主要成果:
- 许多天然产品,包括TCM衍生化合物,显示出对SEVs的显著抑制作用.
- 这些天然产品对猪流行性腹病毒 (PEDV),猪三角冠状病毒 (PDCoV),传染性胃肠炎病毒 (TGEV),猪急性腹综合征冠状病毒 (SADS-CoV) 和猪轮状病毒 (PoRV) 具有不同的作用机制.
- 强调这些药物作为补充或替代疗法的潜力.
结论:
- 自然产品为控制猪中主要的SEV提供了有前途的途径.
- TCM和其他天然化合物可以作为开发新型抗病毒策略的宝贵资源.
- 对这些天然剂的进一步研究可以导致有效的治疗方法和改善猪健康管理.
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