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关于腹膜恶性瘤的INDEPSO-ISPSM共识-高级上皮卵巢癌的管理
Neha Kumar1, Aditi Bhatt2, Snita Sinukumar3
1Department of Gynaecologic Oncology, Amrita Institute of Medical Sciences, Mata Amritanandamayi Marg, RPS City, Sector 88 Faridabad, Faridabad, Haryana 121002 India.
Indian journal of surgical oncology
|February 5, 2026
概括
这一共识为晚期卵巢癌手术提供了指导,在特定情况下推新辅助化疗和高温腹腔内化疗. 它提供了细胞还原手术的技术见解,以改善患者的治疗结果.
科学领域:
- 妇科瘤学 妇科瘤学
- 手术瘤学手术瘤学
- 临床共识 临床共识
背景情况:
- 现有的国际指导方针不足以涵盖晚期上皮卵巢癌的治疗.
- 需要就国家特定的问题和细胞还原手术 (CRS) 的技术方面达成共识.
研究的目的:
- 建立关于高级上皮卵巢癌管理的共识,重点关注目前指南未涵盖的领域.
- 为卵巢癌治疗提供关于细胞还原性手术 (CRS) 和高温腹腔内化疗 (HIPEC) 的建议.
主要方法:
- 修改了德尔菲技术,在48名外科和妇科瘤学家中进行了两轮投票.
- 通过SurveyMonkey传播的7个关键主题的47个闭式问题.
- 共识定义为>70%的选票;强大的共识>90%.
主要成果:
- 在32/47 (68%) 问题上达成共识,在10/47 (21.2%) 问题上达成强烈共识.
- 建议包括新辅助化疗 (NACT) 治疗阳性多细胞学和III-C和IV阶段的特定切除策略.
- 强烈的共识支持将HIPEC添加到高度血清性和粘膜性癌症的间隔CRS中;对于IV-A阶段没有共识.
结论:
- 这一共识为治疗晚期卵巢癌的外科医生提供了宝贵的临床指南.
- 建议涵盖患者选择CRS,NACT和HIPEC,解决CRS的技术方面.
- 进一步的证据可能会导致对这些建议进行修订.
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