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Updated: Feb 6, 2026

Establishment and Validation of a Rat Model of Pulmonary Arterial Hypertension Associated with Pulmonary Fibrosis
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circMFN2 调节IGF2BP3-PDK4以改善肺高血压的作用

Shan-Shan Li1, Miao Guo1, Ying Zhao1

  • 1School of Medicine, Nankai University, Tianjin, China (S.-S.L., M.G., Y.Z., S.H., Y.Y., Y.C., X.J.).

Hypertension (Dallas, Tex. : 1979)
|February 5, 2026
PubMed
概括

在肺高血压 (PH) 中,循环RNA circMFN2 的下调. 在小鼠中恢复circMFN2逆转了PH相关的血管重塑和改善了血液动力学,显示了治疗潜力.

关键词:
RNA,圆形的RNA,圆形的RNA.高血压,肺部高血压,肺部高血压.缺氧 缺氧是指缺氧的情况.肺动脉中的肺动脉.血管改造 血管改造 血管改造

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