乌干达牛肉走廊的牛奶和牛肉中的四环素残留物
Justus Mwesigye1, Justus Kwetegyeka1, Ivan Gumula1
1Department of Chemistry, Faculty of Science, Kyambogo University, Kampala, Uganda.
概括
在乌干达的动物食品中发现了兽医抗生素残留物,特别是四环素. 许多样本超过了安全限值,突出了诸如抗菌素耐药性和更好的药物监测的必要性等风险.
科学领域:
- 食品安全 食品安全
- 兽医药理学 兽医药理学
- 公共卫生 公共卫生
背景情况:
- 动物来源食品 (FOAO) 中的兽医抗生素残留物构成公共卫生风险,包括抗菌素耐药性和肠道微生物群的破坏.
- 环素是广泛使用的兽医抗生素,它们在FOAO中的残留物在全球范围内越来越令人担忧.
研究的目的:
- 调查来自乌干达牛肉走廊的FOAO中六种兽医四环素的发生和含量.
- 评估四环素残留物超过已确定的最大残留物限值 (MRL) 的流行情况.
主要方法:
- 来自纳卡塞克和纳卡索戈拉地区的生牛奶,肌肉组织,肝脏和脏的分析.
- 使用高性能液体染色学 (HPLC) 和液体染色学-双重质谱学 (LC-MS/MS) 来量化氧化,四环素,多,甲,脱环素和甲.
主要成果:
- 在牛奶 (5.3-42.1%) 和牛肉 (7.7-69.2%) 中检测到四环素残留物的中度流行.
- 氧化四环素是最频繁检测到的四环素残留物.
- 很大一部分样品 (5.3-69.2%) 超过了欧盟为氧化环素,甲环素和四环素制定的最大残留量.
结论:
- 这项研究提供了关键的基线数据,即来自乌干达牛肉走廊的销售FOAO中的四环素残留物.
- 结果强调迫切需要加强抗微生物药物管理和严格执行兽药戒断期.
- 在FOAO中对抗微生物残留物的常规国家监测对于保护公共健康至关重要.
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