相关实验视频
Updated: Feb 7, 2026

08:47
Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
13.1K
老年人群中迷你内镜联合内外科手术的结果:匹配对分析
Takahiko Watanabe1,2, Hiroki Ito1,2, Tetsuo Fukuda3
1Department of Urology, Yokosuka Kyosai Hospital, Yokosuka, Japan.
概括
迷你内镜联合内手术 (ECIRS) 对患有结石和尿路结石的老年患者来说是安全有效的. 与年轻患者相比,结果,包括无石头率和并发症,是相似的.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 最少侵入性的手术
- 老年医学 老年医学
背景情况:
- 脏和尿路结石对健康造成重大负担.
- 老年患者可能对手术干预有独特的考虑.
- 迷你内镜联合内手术 (迷你ECIRS) 是一种最少的侵入性方法.
研究的目的:
- 评估迷你ECIRS在患有和尿路结石的老年患者 (≥75岁) 的安全性和有效性.
- 为了比较接受迷你ECIRS的老年和年轻患者队列之间的结果.
主要方法:
- 来自三家日本机构的1303个单一会议迷你ECIRS案件 (2015-2021) 的回顾性分析.
- 患者被分为两组:≥75岁 (n=121) 和<75岁 (n=1182).
- 根据八个手术前和手术内因素对112名老年患者和112名非老年患者进行了匹配分析.
主要成果:
- 在经手术后住院时间方面,在匹配的老年患者和非老年患者之间没有发现显著差异.
- 两组的并发症率在两组之间是可比的.
- 在老年和非老年患者队列中,无石头率 (SFR) 在老年和非老年患者队列中相似.
结论:
- 这项多中心研究表明,迷你ECIRS是75岁及以上患者脏和尿路结石的安全有效治疗方法.
- 老年患者的外科治疗结果与年轻患者的外科治疗结果相似,挑战了以前关于年龄相关外科风险的假设.
相关概念视频
Sign Test for Matched Pairs
417
The sign test for matched pairs offers a robust method for comparing two paired samples, often for the effects of an intervention in one of them. This method is very useful in situations where the underlying distribution of the data is unknown. The test compares two related samples—often pre- and post-treatment measurements on the same subjects—to determine if there are significant differences in their median values.
To conduct the sign test, we first calculate the differences in...
To conduct the sign test, we first calculate the differences in...
417
Wilcoxon Signed-Ranks Test for Matched Pairs
501
The Wilcoxon signed-rank test for matched pairs evaluates the null hypothesis by combining the ranks of differences with their signs. It essentially tests whether the median of the differences in a population of matched pairs is zero. Since the test incorporates more information than the sign test, it generally yields more trustable conclusions. This test also does not require the data to follow a normal distribution, but two conditions must be met for it to be applicable: (1) the data must...
501
Analysis of Population Pharmacokinetic Data
758
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
758
DNA Base Pairing
33.6K
Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
33.6K
Conservation of Small Populations
17.4K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
17.4K
What is Population Genetics?
64.8K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.8K

