严重残疾儿童和成人长期护理机构的抗菌药物管理计划
Nobuhiro Kanie1, Yasuko Kudo2, Koji Fukano3
1Division of Infectious Diseases, Department of Pediatrics, Tokyo Metropolitan Children's Medical Center, Fuchu City, Tokyo, Japan.
概括
在长期护理机构 (LTCFs) 实施抗菌药物管理计划 (ASP) 减少了42%的广谱抗菌药物使用. 这一举措优化了处方,并防止了进一步的耐药性,证明了对资源有限的环境的可行方法.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 医疗保健管理的管理
背景情况:
- 抗微生物药物管理计划 (ASP) 对于打击抗微生物药物耐药性至关重要.
- 长期护理设施 (LTCF) 面临资源限制,阻碍有效实施ASP.
- 这项研究评估了LTCFs可行的ASP模型.
研究的目的:
- 评估扩展ASP对LTCF中的抗菌素处方的影响.
- 为了确定干预后抗菌素使用和耐药率的变化.
主要方法:
- 在日本LTCF中进行了一项准实验性研究.
- 干预措施包括教育,治疗手册,事先授权和前性审计.
- 对抗微生物药物治疗日和抗药性率的数据进行了干预前后的比较.
主要成果:
- 观察到口服广谱抗微生物药物 (宏类,诺类,第三代类) 的使用量有显著的下降.
- 埃舍里希亚大肠杆菌和 Pseudomonas aeruginosa 对美罗和勒沃素的耐药性率保持稳定.
- 这项干预措施导致口服广谱抗菌素使用量下降了42%.
结论:
- 将ASP专业知识从急性护理设施扩展到LTCF是有效的.
- 这种模型成功地减少了LTCF中广泛的抗菌素处方.
- 这种方法对优化抗微生物药物的使用和对抗LTCF的耐药性非常有希望.
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