基于Ormocer的临床性能与以甲基酸盐为基础的常规树脂复合材料在后续修复中的临床性能:系统性审查和网络元分析
Alain Manuel Chaple Gil1, Laura Pereda Vázquez2, Meylin Santiesteban Velázquez3,4
1Universidad Autónoma de Chile. Facultad de Ciencias de la Salud, Santiago, Chile.
概括
基于Ormocer的树脂复合材料在后部修复中表现出与传统复合材料相比的临床性能. 这些材料在36个月内提供了类似的边际适应性,保留性和断裂性.
科学领域:
- 牙科材料科学 牙科材料科学
- 恢复性牙科 恢复性牙科
- 生物材料是一种生物材料.
背景情况:
- 基于Ormocer的树脂复合材料是传统甲基酸基材料的替代品.
- 对传统复合材料中的潜在双A (BPA) 相关化物存在担忧.
- 需要临床性能数据来比较后部修复中的这些材料类型.
研究的目的:
- 系统地审查和网络分析基于ormocer的临床性能与传统树脂复合材料的临床性能.
- 为了比较和排列这些材料用于后来的I和II类修复.
- 评估结果,如边际适应,保留和断裂.
主要方法:
- 在2025年10月之前,对多个数据库进行系统搜索.
- 包括随机对照和前性临床试验,随访时间≥6个月.
- 使用USPHS或外国直接投资标准对主要结果 (边际适应,保留,断裂) 的网络元分析 (NMA).
主要成果:
- 包括12个试验 (1158次修复) 在内.
- 与传统复合材料相比,基于Ormocer的复合材料在所有时间点 (6-36个月) 中没有显著的差异,对于边际适应,保留或骨折.
- 治疗排名表明了概率等价性,证据的确定性中等.
结论:
- 包括混合体和散装填充类型在内的基于ormocer的复合材料,表现出与传统甲基酸盐的复合材料相当的临床性能.
- 没有bis-GMA的ormocer配方可以减少BPA暴露,而不会影响临床结果.
- 建议进行更长的后续研究,以进一步验证这些发现.
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