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Updated: Feb 7, 2026

An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use

An Automated Radiosynthesis of [⁶⁸Ga]Ga-FAPI-46 for Routine Clinical Use

Published on: May 24, 2024

在骨的血管性瘤中FAPI摄入量

Amin Saber Tanha¹, Nasrin Raeisi, Farivash Karamian

¹Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Clinical nuclear medicine

|February 5, 2026

概括

这项案例研究突出了前列腺癌成像过程中骨髓的无血管亡的潜在错误阳性. 177Lu-PSMA和68Ga-FAPI PET/CT扫描显示在这种情况下的非典型吸收.

科学领域:

核医学就是核医学.
在瘤学瘤学.
放射学放射学是一门学科.

背景情况:

转移性割抵抗性前列腺癌 (mCRPC) 的管理包括先进的成像.
乳-177前列腺特异性膜抗原 (177Lu-PSMA) 治疗和-68纤维细胞激活蛋白抑制剂 (68Ga-FAPI) PET/CT用于诊断和治疗监测.
图像学中的非典型发现需要仔细解释.

研究的目的:

报告一个转移性割抵抗性前列腺癌的病例,有不寻常的成像发现.
为了调查177Lu-PSMA治疗随访期间观察到的非典型吸收的原因.
为了说明使用PSMA和FAPI标记剂在无血管缩中的潜在假阳性解释.

主要方法:

一名患有mCRPC和先前肝脏干扰的患者接受了177Lu-PSMA治疗.
在第三个周期后的治疗后扫描分析了吸收模式.
使用68Ga-FAPI-46进行了PET/CT的再定位.
磁共振成像 (MRI) 用于相关性和确认.

主要成果:

在177Lu-PSMA治疗后扫描过程中,在左脚观察到非典型的吸收.
同一个区域在68Ga-FAPI-46 PET/CT上显示了FAPI吸收.
核磁共振 (MRI) 的相关性证实了骨的无血管缩.
这表明了对177Lu-PSMA-617和68Ga-FAPI-46.6的假阳性摄入.

结论:

骨的血管性亡可以导致177Lu-PSMA和68Ga-FAPI PET/CT成像中的假阳性摄取.
放射科医生和核医学医生应该意识到这种潜在的陷.
与其他成像方法 (如MRI) 进行仔细的相关性对于准确的诊断至关重要.

关键词:

在SPECT/CT测试中,骨质结核病的结核病.陷陷是一个陷.无线电连接体治疗疗法他们是天文学家.

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