在眼内透镜植入后,马芬综合征患者的折射成长 带有眼内透镜植入后的眼内透镜
Xinyao Chen1,2,3, Xin Shen1,2,3, Wannan Jia1,2,3
1Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
Journal of cataract and refractive surgery
|February 5, 2026
概括
在植入眼内透镜 (IOL) 后,Marfan综合征 (MFS) 患者的折射增长与眼内透镜 (EL) 进行了插入,遵循了对数模式. 手术后视力敏度和折射状态显著影响这种生长,需要仔细监测.
科学领域:
- 眼科医生 眼科 眼科
- 遗传学 遗传学 是一个
- 生物医学工程 生物医学工程
背景情况:
- 马凡综合征 (MFS) 是一种影响结缔组织的遗传性疾病.
- 乳眼 (EL) 是MFS中常见的眼部表现,通常需要眼内透镜 (IOL) 植入.
- 了解这些患者在IOL植入后的折射增长对于长期视觉结果至关重要.
研究的目的:
- 在EL.MFS患者中,评估IOL植入后的折射生长模式.
- 在这个特定的患者群体中确定影响折射误差进展的因素.
主要方法:
- 进行了一项回顾性队列研究,涉及了经过IOL植入的EL的MFS患者.
- 眼部生物识别参数和球体等价值 (SE) 在手术前和手术后记录下来.
- 使用多变量通用估计方程 (GEE) 模型计算和分析折射增长率 (RRG3),以确定预测因素.
主要成果:
- 这项研究分析了232名患有EL的MFS患者的374只眼睛.
- 折射增长跟随着对数进展,平均RRG3为-14.1±10.2D.
- 在较年轻的患者 (≤8岁) 中,术后近视和视敏度影响了RRG3. 在老年患者 (8-15岁) 中,RRG3与术后SE相关. 手术时的年龄,IOL固定和手术前的生物识别并不是显著的预测因素.
结论:
- 在初级IOL植入后,MFS眼睛与EL的折射生长表现出对数进展.
- 手术后的折射状态和最佳校正的视力敏度是折射生长的重要决定因素.
- 建议进行战略性的不足纠正和认真的术后监测,以实现最佳管理.
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