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Updated: Feb 7, 2026

In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
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使用PEP-1-CAT增强线粒可以减轻小鼠血管炎症和异构发生

Shuang Wei1,2,3, Lei Zhang3, Xuan-Ren Wang2,3

  • 1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.

Inflammation
|February 5, 2026
PubMed
概括

这项研究表明,抗氧化剂PEP-1-Catalase (CAT) 通过增强线粒细胞衰老 (mitophagy) 来改善血管衰老,这是一种清除受损线粒体的过程. 这减少了炎症和氧化应激,为动脉样硬化提供了潜在的治疗方法.

关键词:
动脉样硬化是一种动脉样硬化.线粒体损伤导致线粒体损伤.线粒细胞衰变 - - 线粒细胞衰变 (mitophagy) 是一种这就是NF-κBB.在NLRP3炎症酶组中,NLRP3炎症在PEP-1-CAT中使用PEP-1-CAT.

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