儿童和青少年:呼吸道感染和长期影响纵向研究 (CARE研究):研究协议
Mark McMillan1,2, Rebecca Beazley3, Nan Vasilunas4
1University Department of Paediatrics, Women's and Children's Hospital Network, North Adelaide, South Australia, Australia.
PloS one
|February 5, 2026
概括
这项研究追踪了澳大利亚儿童和青少年的COVID后病情 (PCC) 和急性后病情 (PAS). 它比较了COVID-19和流感后的结果,以告知临床管理.
科学领域:
- 儿童传染病 儿童传染病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 长期COVID或COVID后状态 (PCC) 影响儿童和青少年超出急性SARS-CoV-2感染.
- 在这种年龄组中,流感后的急性后续症状 (PAS) 也是令人担忧的.
- 澳大利亚儿童在Omicron变种期间的PCC和流感后的PAS数据有限.
研究的目的:
- 确定澳大利亚儿童和青少年中PCC的累积发病率,大流行后5年开始.
- 确定流感感染后儿童和青少年PAS的累积发病率.
主要方法:
- 纵向队列研究招募0-18岁的南澳大利亚人,他们最近感染了SARS-CoV-2或流感.
- 在线调查在基线,3,6和12个月感染后.
- 使用验证的工具 (PedsQL,疲劳量表,POTS分数) 和适应的世卫组织定义用于PCC/PAS识别.
主要成果:
- 这个部分不在所提供的摘要中.
结论:
- 解决了在Omicron循环期间儿童PCC和PAS的知识差距.
- 将COVID-19和流感后的后急性后果进行比较,帮助儿童感染后的临床管理策略.
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