儿童牙科手术的最佳麻醉深度:一项随机试验证实了BIS 60通过闭环TCI的有效性
Qiu-Fang Jin1, Ze-Xiu He1, Dong-Fang Xu1
1Department of Anesthesiology, School and Hospital of Stomatology, Hebei Medical University, Shijiazhuang, China.
The Journal of craniofacial surgery
|February 5, 2026
概括
在接受牙科手术的儿童中,在闭环麻醉时保持双光谱指数 (BIS) 60 显著加快了恢复和出院的速度. 这种优化的麻醉深度改善了患者的治疗结果和术后效率.
科学领域:
- 麻醉学 麻醉学
- 儿科牙科 儿科牙科
- 医疗器械 医疗器械
背景情况:
- 小孩子的牙科手术通常需要全身麻醉,因为焦虑和痛苦.
- 这些手术的最佳麻醉深度还没有得到很好的定义.
- 闭环目标控制输注 (TCI) 提供精确的麻醉输送.
研究的目的:
- 在牙科手术期间,在学龄前儿童中使用闭环TCI评估麻醉的最佳深度.
- 评估不同双谱指数 (BIS) 目标对手术内稳定性和恢复的影响.
- 确定最有效的BIS值来平衡麻醉深度和恢复时间.
主要方法:
- 一项随机,双盲,受控试验涉及60名接受牙科手术的儿童 (3-6岁).
- 参与者被指派使用闭环TCI系统保持BIS值为50,55,或60.
- 主要结局包括心率 (HR) 和平均动脉压 (MAP);次要结局包括手术持续时间和康复指标.
主要成果:
- 在BIS组之间没有发现HR或MAP的显著差异.
- 手术持续时间和普罗波福尔剂量在各组之间没有显著差异.
- 与BIS 50相比,较低的BIS目标 (55和60) 导致首次眼睛打开,输出和排出的时间明显缩短.
结论:
- 闭环TCI的BIS目标60 (±5) 确保了儿童牙科手术的足够麻醉深度.
- 这一策略显著减少了患者的康复和出院时间.
- 优化的麻醉深度可以提高儿科患者的恢复和术后效率.
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