同时脉冲场切除和左心室附带关闭的可行性,程序效率和早期成像结果:一个前性的单中心研究
Brandon Doty1, Mohamed Mraiyan2,1, Ganesh Nair1
1Arrhythmia Research Group, Jonesboro, AR, USA.
概括
对于心房动 (AF) 和左心房关闭 (LAAC) 的联合脉冲场切除 (PFA) 是一种安全的,单一程序的方法. 这项研究显示了有利的早期结果,支持其在常规实践中的可行性.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 心房的管理需要控制心律失常和降低中风风险.
- 同时的脉冲场切除 (PFA) 和左心室尾关闭 (LAAC) 提供了一个单一程序解决方案.
- 在临床实践中评估这种综合方法的安全性和可行性至关重要.
研究的目的:
- 评估PFA和LAAC联合工作流程,安全性和可行性.
- 评估这种综合程序方法的早期临床结果.
- 为了确定LAAC在消除后预防血栓栓塞事件的有效性.
主要方法:
- 对接受零光学PFA与低光学LAAC的患者进行前性分析.
- 使用CT成像和AI进行程序前规划,用于设备选择和着陆区评估.
- 单个穿越性穿刺,使心内回声心脏成像,PFA导管和LAAC罩的连续使用成为可能.
主要成果:
- 包括209名患者 (平均年龄为76.5岁) 患有各种类型的AF (发作性,持久性,de novo).
- 高成功率的LAAC (94%单一设备,100%充足的密封) 与最小的并发症 (没有重大不良事件).
- 早期的随访显示4.7%的小泄漏率,两个设备相关的血栓没有中风,并在同一天出院.
结论:
- 结合PFA和LAAC是一种可行且安全的AF管理策略.
- 早期有利的结果表明这种综合方法的潜力.
- 建议进行进一步的多中心研究,以验证发现并标准化工作流程,以便更广泛地采用.
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