肠道微生物群和果牛的代谢适应性 Pomacea canaliculata:对寒冷耐受性的洞察
Jing Liu1, Hua Wang2, Jing Gao3
1College of Bioscience and Biotechnology, Hunan Agricultural University, No. 1 Nongda Road, Changsha, Hunan 410128, China.
Ecotoxicology and environmental safety
|February 5, 2026
概括
肠道微生物通过促进脂质新陈代谢和能量生产来提高果牛的寒冷耐受性. 这种适应对于在恶劣,寒冷的环境中航行的入侵物种至关重要.
科学领域:
- 微生物生态学 微生物生态学
- 环境适应 环境适应
- 动物生理学 动物生理学
背景情况:
- 肠道微生物群在入侵物种适应具有挑战性的环境中发挥着关键作用.
- 牛中肠道微生物群介导的寒冷耐受性和新陈代谢的分子机制尚不清楚.
研究的目的:
- 研究肠道微生物群在果牛Pomacea canaliculata的耐寒性中的作用.
- 阐明肠道微生物调节宿主新陈代谢和适应寒冷的分子机制.
主要方法:
- 综合生理学测量,蛋白质组学,代谢组学和微生物社区分析的多学科方法.
- 高度 (H组) 和低度 (G组) 果牛在寒冷压力下 (0°C60小时) 的比较.
- 分析蛋白质表达,代谢物概况和肠道微生物组成.
主要成果:
- 与低度牛 (G组) 相比,高度牛 (H组) 在寒冷压力下表现出明显更高的生存率,能量水平和抗氧化酶活性.
- 蛋白质组分析显示,H组中参与脂肪酸合成和能量代谢的蛋白质 (例如FABP,PDHE1,AKR) 的上调调节.
- 组H显示了与心理和脂质代谢相关的细菌的丰富性增加,与长链脂肪酸合成的增加和能量供应的增强相关.
结论:
- 肠道微生物群通过调节宿主新陈代谢,特别是脂质合成和能量生产,显著促进果牛的耐寒性.
- 宿主蛋白质和代谢物的微生物调节增强了能量供应和细胞膜流动性,这对于适应寒冷条件至关重要.
- 这些发现提供了入侵物种应对气候变化和寒冷环境的适应策略的见解.
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