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Updated: Feb 7, 2026

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从Cercis chinensis花中利用深层环氧溶剂进行超声波辅助的黄酸提取:优化,表征,动力学和生物活性
Penghua Shu1, Na Wang2, Xinfeng Fan2
1Food and Pharmacy College, Xuchang University, Xuchang 461000, Henan, China; Collaborative Innovation Center of Functional Food by Green Manufacturing, Xuchang 461000, Henan, China; School of Life Sciences, Henan University, Kaifeng 475004, Henan, China.
Ultrasonics sonochemistry
|February 5, 2026
概括
超声波辅助的深度欧学溶剂提取有效地从Cercis chinensis花中恢复高产量的黄酸. 这种环保方法提供了卓越的抗氧化活性和溶剂可回收性,为天然产品提取提供了可持续的方法.
科学领域:
- 自然产品化学 自然产品化学
- 绿色化学 绿色化学
- 生物技术是生物技术.
背景情况:
- 中华花是生物活性化合物的丰富来源,特别是黄类化合物.
- 传统的提取方法往往缺乏效率,并使用苛刻的溶剂.
- 开发可持续和有效的提取技术对于利用花资源至关重要.
研究的目的:
- 开发和优化一种高效和环保的超声波辅助深度欧溶剂 (UAE-DES) 提取方法,从Cercis chinensis花中提取黄类药物.
- 为了比较阿联-DES方法与传统的乙醇提取.
- 为了描述提取的黄酸盐,并评估该方法的抗氧化特性和可持续性.
主要方法:
- 选了17个深度浸泡溶剂 (DES) 系统,其中L-proline-乳酸 (DES-11) 被确定为最佳的.
- 使用响应表面方法优化阿联-DES参数 (超声波温度,时间,含水量).
- 扫描电子显微镜 (SEM) 用于细胞干扰分析.
- 提取动力学建模和明显激活能量的确定.
- 使用UPLC-timsTOF-MS.识别黄类药物.
- 通过激素清除试验进行抗氧化活性评估.
- 使用宏树脂进行DES回收和可重复使用性评估.
主要成果:
- 与60%乙醇 (13.65 mg/g) 相比,L-proline-乳酸DES实现了显著更高的黄类产量 (56.53 mg/g).
- 在优化的阿联-DES条件下,黄素的最大度为95.84 mg/g.
- SEM证实了DES-11的大量细胞破坏,增强了黄类的释放.
- 提取动力学遵循伪第一阶模型,表明扩散控制的机制.
- 在DES提取物中首次发现了34种黄类.
- 德斯提取物表现出卓越的抗氧化活性.
- 在四个重复使用周期后,DES回收实现了86.64%的黄酸回收,效率>84.93%.
结论:
- 阿联-DES方法是高效和环保的,用于从Cercis chinensis花中提取黄.
- 这种方法为传统方法提供了一个可持续的替代方案,产生高价值的天然抗氧化剂.
- 该方法在天然产品的提取和利用中显示出工业应用的巨大潜力.
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