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Updated: Feb 7, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
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状网状细胞中的机械传导:依赖于基质刚性的Rho/ROCK反应

Ruotian Du1, Jing Ji2, Dongyan Li2

  • 1Key Laboratory of Biomechanics and Mechanobiology, Ministry of Education, National Medical Innovation Platform for Industry-Education Integration in Advanced Medical Devices (Interdiscipline of Medicine and Engineering), School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China; State Key Laboratory of Nonlinear Mechanics, Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China.

Journal of biomechanics
|February 5, 2026
PubMed
概括

基质刚性通过改变Rho/ROCK通路影响状网状细胞 (TMCs),影响眼内压力 (IOP) 调节,这对玻璃眼瘤至关重要. 抑制这种途径可以缓解TMCs中度诱导的变化.

关键词:
眼光障碍 眼光障碍 眼光障碍 眼光障碍机械生物学 机械生物学在Rho/ROCK路径上.基板的刚性 基板的刚性脊柱状网状网状细胞的细胞结构.

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