相关实验视频
Updated: Feb 7, 2026
03:36
Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
847
马的第三只眼皮中的透明细胞状细胞癌
Daniel R Rissi1, Ricardo E Mendes1
1Athens Veterinary Diagnostic Laboratory, Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Journal of comparative pathology
|February 5, 2026
概括
这项研究报告了马的第三只眼中第一个清晰细胞状细胞癌 (SCC) 病例. 这种局部侵入性瘤虽然很少见,但强调了对马类眼部瘤进行仔细的组织学评估的必要性.
科学领域:
- 兽医病理学 兽医病理学
- 马类瘤学 马类瘤学
- 眼科医生 眼科 眼科
背景情况:
- 状细胞癌 (SCC) 是马中最常见的眼球和眼周瘤.
- SCC是局部侵入性的,经常复发,很少会转移.
- 非典型的SCC亚型可能会带来诊断挑战,需要进行彻底的组织学检查.
研究的目的:
- 描述一种影响马的第三只眼的清细胞SCC新型病例.
- 为这种罕见的瘤亚型提供详细的组织学和免疫组织化学发现.
- 为了解马类眼部瘤做出贡献.
主要方法:
- 眼球质量的外科切除用于组织学评估.
- 瘤组织的显微镜检查,包括细胞形态和排列.
- 免疫组织化学染色用于胰岛素 (AE1/AE3),周期性酸-Schiff,Mayer粘性和苏丹IV染色.
- 对血管侵袭和相邻的粘膜变化的组织学评估.
主要成果:
- 在16岁的四分之一马的第三只眼皮中发现了一种清晰细胞SCC.
- 新生态细胞表现出清晰的细胞质,明显的边界,以及状分化的特征.
- 发现了高的线粒细胞计数 (每2.37mm2中的23个) 和血管侵袭的证据.
- 新生细胞对胰岛素激素有强烈的阳性,对粘液和脂质有负面.
- 邻近的第三只眼粘膜显示出失塑性上皮质斑块.
结论:
- 这一病例是首次在家禽中报告了眼球或眼周透明细胞SCC的病例.
- 清晰细胞SCC应在马类眼部瘤的差异诊断中考虑.
- 准确的诊断依赖于全面的组织学和免疫组织化学分析.
相关概念视频
01:07What are Cells?
201.2K
Cells are the smallest and basic units of life, whether it is a single cell that forms the entire organism, e.g., in a bacterium or trillions of them, e.g., in humans. No matter what organism a cell is a part of, they share specific characteristics.
Basic Characteristics of Cells
A living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment.
Furthermore, a living cell possesses genetic information...
Basic Characteristics of Cells
A living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment.
Furthermore, a living cell possesses genetic information...
201.2K
01:15What are Cells?
49.2K
Cells are the smallest and basic units of life, whether it is a single cell that forms the entire organism, e.g., in a bacterium, or trillions of them, e.g., in humans. No matter what organism a cell is a part of, they share specific characteristics.
Basic Characteristics of Cells
A living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment.
Furthermore, a living cell possesses genetic information...
Basic Characteristics of Cells
A living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment.
Furthermore, a living cell possesses genetic information...
49.2K
02:03What is Cell Signaling?
131.0K
Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
131.0K
02:58Chemistry of the Cell
48.1K
The cell is chemically composed of water, organic molecules and inorganic ions.
Water
The polarity of the water molecule and its resulting hydrogen bonding makes water a unique substance with special properties that are intimately tied to the processes of life. Life originally evolved in an aqueous environment, and most of an organism’s cellular chemistry and metabolism occur inside the aqueous contents of the cell’s cytoplasm. Special properties of water are its high heat capacity...
Water
The polarity of the water molecule and its resulting hydrogen bonding makes water a unique substance with special properties that are intimately tied to the processes of life. Life originally evolved in an aqueous environment, and most of an organism’s cellular chemistry and metabolism occur inside the aqueous contents of the cell’s cytoplasm. Special properties of water are its high heat capacity...
48.1K
02:41Concentration Cells
25.9K
A concentration cell is a type of a voltaic cell constructed by connecting two almost identical half-cells, both based on the same half-reaction and using the same electrode, differing only in the concentration of one redox species. A concentration cell's potential, therefore, is determined only by the concentration difference of the particular redox species.
Consider the following voltaic cell:
Consider the following voltaic cell:
25.9K
01:22Cell Size
128.9K
Cell sizes vary widely among and within organisms. Bacterial cells range between 1-10 micrometers (μm)and are considerably smaller than most eukaryotic cells. The smallest bacteria are 0.1 μm in diameter—about a thousand times smaller than eukaryotic cells, which typically range from 10-100 μm.
Surface Area
Cells can take in nutrients and water via diffusion through the plasma membrane itself or through specific channels in the membrane. The area of the membrane surrounding...
Surface Area
Cells can take in nutrients and water via diffusion through the plasma membrane itself or through specific channels in the membrane. The area of the membrane surrounding...
128.9K