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Updated: Feb 7, 2026

Production of a SARS-CoV-2 Virus-Like-Particle System to Investigate Viral Life Cycles In Vitro
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Published on: June 6, 2025

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针对 chikungunya 病毒和 SARS-CoV-2 的生物工程仿真 VLP 在小鼠中显示出高免疫性

Vedita Anand Singh1, Sanketkumar Nehul1, Ankita Saha1

  • 1Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.

Biochemical and biophysical research communications
|February 5, 2026
PubMed
概括

这项研究介绍了化学阿尔法病毒-冠状病毒类粒子 (ChAC-VLPs),一种针对奇孔尼亚病毒 (CHIKV) 和SARS-CoV-2的新型双价疫苗. 在临床前模型中,ChAC-VLP显示出对两种病毒的显著中和能力.

关键词:
奇孔古尼亚病毒 (CHIKV)仿真病毒样颗粒 (Chi-VLPs) 是一种类似于仿真病毒的微粒.包裹中的糖蛋白质.中和抗体反应的反应.受体结合域 (RBD) 是指受体结合域.复合疫苗技术是复合疫苗的技术.这就是SARS-CoV-2病毒.

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