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Updated: Feb 7, 2026

Development of a Larval Zebrafish Infection Model for Clostridioides difficile
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Development of a Larval Zebrafish Infection Model for Clostridioides difficile

Published on: February 14, 2020

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5,6合的异环胆酸盐衍生物作为Clostridioides difficile的子发芽抑制剂

Shiv K Sharma1, Jacqueline R Phan2, Efren Heredia2

  • 1Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, United States.

Bioorganic & medicinal chemistry
|February 5, 2026
PubMed
概括

开发了新的胆盐类似物,以预防Clostridioides difficile感染 (CDI). 在动物模型中,索 (6b) 等异环化合物在预防CDI方面表现出稳定性和有效性.

关键词:
胆盐类似的类似物克洛斯特里迪奥伊德斯困难菌抑制剂的抑制剂子的发芽 子的发芽

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