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Updated: Feb 7, 2026

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IL22支持老鼠和人类肝细胞的长期扩张

Bing Li1, Ren Guo2, Shitong Wang3

  • 1School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China.

Journal of hepatology
|February 5, 2026
PubMed
概括

介质素22 (IL22) 能够使小鼠和人类肝细胞在体外大规模扩张. 这种细胞因子激活了Stat3-Bhlha15/Arntl2通路,将肝细胞分化为可扩展的原始细胞,用于未来的临床应用.

关键词:
一个叫Arntl2的.这就是Bhlha15的意义.细胞因子细胞因子IL2222 这是一个很好的方法.统计 统计 统计扩张 扩张 扩张肝脏脱差分化的情况.肝细胞 肝细胞

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