心理测量分析辅助生殖技术 (ART) 怀孕:来自nuMoM2b队列的见解
Stylianos Vagios1, Christopher K Arkfeld2, Andriana H Velmahos3
1Division of Reproductive Endocrinology and Infertility, Vincent Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Suite 10A, Boston, MA, 02114, USA; Department of Obstetrics and Gynecology, Tufts Medical Center, Boston, MA, USA.
Fertility and sterility
|February 5, 2026
概括
通过辅助生殖技术 (ART) 怀孕的女性在怀孕期间表现出类似的抑郁和感知压力的比率,与那些自然怀孕的女性相比. 在怀孕早期,人工智能受孕似乎不会增加母亲的心理健康风险.
科学领域:
- 生殖医学和孕产妇健康
- 怀孕期间的心理健康
背景情况:
- 辅助生殖技术 (ART) 越来越多地用于怀孕.
- 了解怀孕期间ART怀孕对心理健康的影响至关重要.
研究的目的:
- 调查通过ART怀孕和孕期母亲抑郁或焦虑之间的关联.
- 为了比较通过ART与自然受孕怀孕的无孕妇女的心理健康结果.
主要方法:
- 预期无卵性妊娠结果研究的二次分析:监测即将成为母亲 (nuMoM2b).
- 通过ART怀孕的366名女性与自然怀孕的8922名女性进行了比较.
- 在第一和第三个三个月评估母亲的抑郁症状 (EPDS),焦虑 (STAI) 和感知压力 (PSS).
主要成果:
- 未经调整的分析显示,ART组的抑郁和压力得分较低.
- 然而,经过调整后的分析显示,在ART组和非ART组之间,在两个季度中,显著的抑郁症状的发生率相似.
- 在调整后,两组之间感知到的压力和焦虑 (STAI) 水平是可比的.
结论:
- 通过ART的怀孕与未经辅助的怀孕相比,在怀孕早期和晚期与类似水平的抑郁症状有关.
- 在怀孕期间感知到的压力在通过ART怀孕的女性和自然怀孕的女性之间也是可比的.
- 在怀孕期间,ART怀孕似乎不是增加抑郁或焦虑的独立风险因素.
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