双重乳液凝中含有物理素,稳定由基尼交叉连接的碳氧甲基基托和乳清蛋白分离合物:突出优越的稳定性和持续释放性
Miaomiao Han1, Ya Zhao1, Li Li1
1School of Agricultural Engineering and Food Science, Shandong University of Technology, Xincun West Road, Zibo, Shandong Province, 255000, PR China.
International journal of biological macromolecules
|February 5, 2026
概括
基尼交叉链接的碳素甲基基托和乳清蛋白分离合物有效地稳定了双乳液凝,用于输送植物. 这些凝提供了更好的储存稳定性和持续的肠道释放生物活性化合物.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物材料工程 生物材料工程
- 营养药物输送系统 营养药物输送系统
背景情况:
- 聚氨酸 (PC) 是一种有价值的生物活性化合物,储存稳定性有限,在有针对性的输送方面存在挑战.
- 开发有效的输送系统对于提高PC等水友性化合物的稳定性和生物可用性至关重要.
研究的目的:
- 开发和表征基尼交联的甲基基 (CMCS) 和乳清蛋白分离物 (WPI) 结合物.
- 为了利用这些合物稳定水-油-水 (W1/O/W2) 双乳液凝 (DEGs) 来改善 phycocyanin (PC) 封装和受控释放.
主要方法:
- 制备各种质量比的CMCS-WPI结合物,与基尼 (GP) 交联.
- 形成双乳液凝 (DEGs),其中包含素 (PC).
- 评估封装效率 (EE),储存稳定性,质性,纹理性质和体外释放动力学.
主要成果:
- FTIR证实了CMCS和WPI之间由GP交联诱导的共价键.
- 最佳的DEGs (1.5%CMCS,2.5%WPI) 实现了高EE (99.89%),小滴滴大小 (8.62μm) 和优良的纹理特性.
- 在试验室消化显示PC在模拟胃液中的释放最小,在Fickian扩散 (Korsmeyer-Peppas模型) 之后,在肠液中持续释放.
结论:
- 基尼平交叉连接的CMCS-WPI结合物有效地稳定DEG,增强PC存储的稳定性.
- 开发的DEGs提供了一个强大的平台,用于向肠道输送水友生物活性化合物.
- 这种方法提供了一种有前途的策略,可以提高在食品和制药行业中植物的有效性和应用.
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