乳腺动脉化及其与心血管疾病和全因死亡率的关联的系统审查和元分析
Emma Christensen1, Christen Hillenbrand1, Anugraha Kutty1
1Department of Medicine, Penn State College of Medicine, Hershey, PA.
The American journal of cardiology
|February 5, 2026
概括
乳腺动脉化 (BAC),检测到乳房影像,与更高的心血管疾病 (CVD) 的风险和女性的死亡率有关. 需要进一步的研究来确认其在风险分层方面的临床实用性.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 流行病学 流行病学
背景情况:
- 乳腺动脉化 (BAC) 是中枢动脉的化,通常在乳房影像上偶然检测到.
- 以前的研究表明,BAC与心血管疾病 (CVD) 风险增加之间存在潜在的关联.
- 了解这种关联可以帮助女性对心脏病风险分层.
研究的目的:
- 系统地审查和元分析BAC和心血管疾病风险因素,心血管结果和死亡率之间的关联.
- 量化与BAC存在相关的各种心血管事件和死亡率的风险.
- 评估BAC作为女性心血管疾病风险标志物的临床实用性.
主要方法:
- 进行了系统的文献搜索,以确定相关研究.
- 使用随机效应模型进行了元分析,以计算95%置信区间 (CI) 的风险比率 (RR) 和赔率比率 (OR).
- 在包括的45项研究中 (68,584名女性) 使用Q值和I2统计数据来评估异质性.
主要成果:
- BAC与糖尿病,高血压和高脂血症的几率增加有关.
- BAC与发生性中风,心力衰竭,心脏死亡,动脉样硬化心血管疾病 (ASCVD) 和全因死亡率的风险更高有关.
- 在BAC和吸烟之间观察到负相关性,BAC与已知的心血管疾病有关.
结论:
- 乳房镜检测到的BAC可以作为女性心血管疾病风险和死亡率升高的有价值指标.
- 这些发现突显了BAC在心血管疾病风险分层中的潜力.
- 建议对BAC评估方法进行标准化,以便在未来的研究中确认其临床实用性.
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