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Updated: Feb 7, 2026

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
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Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS

Published on: November 8, 2015

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一个用 DESI-MS/MS 构建的干血斑点的高通量检测平台

Siqi Gao1, Jinhui Zhao2, Yue Guan3

  • 1Department of Sanitary Inspection, School of Public Health, Harbin Medical University, Harbin, 150086, P. R. China; Shanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus, Shanghai, 201499, P. R. China.

Analytica chimica acta
|February 5, 2026
PubMed
概括

这项研究优化了使用脱电喷雾质谱法 (DESI-MS/MS) 分析干血斑点 (DBS) 的方法. 开发的协议能够准确检测代谢变化,证明了对新生儿查等临床应用的实用性.

关键词:
溶解电喷剂质谱测量 溶解电喷剂质谱测量干燥的血液斑点 干燥的血液斑点代谢特征 代谢特征超高性能液体色谱学 超高性能液体色谱学

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