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Updated: Feb 7, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
13:58

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells

Published on: October 22, 2012

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共享的PRAME表位是NUT癌症中T细胞的点

Jeffrey L Jensen1,2, Sara K Peterson2,3, Maria J Sambade2

  • 1Division of Medical Oncology, The University of North Carolina at Chapel Hill Department of Medicine, Chapel Hill, North Carolina, USA.

Journal for immunotherapy of cancer
|February 5, 2026
PubMed
概括

这项研究确定PRAME是NUT癌症中关键的癌症抗原,由BRD4::NUTM1瘤基因驱动. 针对PRAME的免疫疗法显示出治疗这种罕见而致命的癌症的前景.

关键词:
抗原受体设计的设计双特异性T细胞参与者 - BiTE头部和部癌症 头部和部癌症肺癌 肺癌 是 一种 肺癌.T细胞受体 - - TCR 细胞受体

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