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Updated: Feb 7, 2026

Analyzing Supercomplexes of the Mitochondrial Electron Transport Chain with Native Electrophoresis, In-gel Assays, and Electroelution
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Published on: June 1, 2017

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过渡性蛋白质结构指导膜超复合体中电子运输的表面扩散通路

Chun Kit Chan1, Jonathan Nguyen1, Corey F Hryc2

  • 1School of Molecular Sciences, Biodesign Institute, Arizona State University, Tempe, AZ, USA.

Nature communications
|February 5, 2026
PubMed
概括

线粒体超级复合体使用无序的链引导氧化还原蛋白,提高了30%的能量转换效率. 这种重新折叠引导的扩散机制优化了跨膜的电子传输.

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Electron Transport Chains

The final stage of cellular respiration is oxidative phosphorylation that consists of two steps: the electron transport chain and chemiosmosis. The electron transport chain is a set of proteins found in the inner mitochondrial membrane in eukaryotic cells. Its primary function is to establish a proton gradient that can be used during chemiosmosis to produce ATP and generate electron carriers, such as NAD+ and FAD, that are used in glycolysis and the citric acid cycle.
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Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
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