超越CRISPR:对CAR-NK细胞进行下一代精密工程,以提高持久性,贩运和瘤根除

Aiyun Dong1, Hamed Soleimani Samarkhazan2, Farzaneh Tavakoli3,4

  • 1The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi Province, China. 13834541328@163.com.

Cancer cell international
|February 6, 2026
PubMed
概括

下一代基因编辑工具,包括基础和主要编辑器,克服了CRISPR-Cas9的局限性,用于增强的仿真抗原受体自然杀手 (CAR-NK) 细胞疗法. 这些进展承诺更安全,更有效的CAR-NK细胞用于治疗各种癌症.

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