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Updated: Feb 7, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
10:49

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

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2-阿米诺佐提亚:为氨酸激酶向性抗癌剂的特权支架

Rani D Navle1, Nirmala V Shinde1, Arti S Raut1

  • 1Department of Pharmaceutical Chemistry, SMBT College of Pharmacy, Nashik, India.

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
|February 6, 2026
PubMed
概括

2-阿米诺索衍生物显示出作为抗癌剂的前景,向CDK和EGFR等酶,以及非酶标,如BCL-2. 药物化学研究重点是优化替代品,以提高针对性癌症治疗的疗效和特异性.

关键词:
这是一种2-Aminobenzothiazole.抗癌剂是一种抗癌剂.药物设计 药物设计异环结构的脚手架 异环结构的脚手架激酶的信号传递方式结构活动关系 (SAR)有针对性的癌症治疗.铁氨酸激酶抑制剂 铁氨酸激酶抑制剂抑制了VEGFR-2/EGFR的发生.

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