作为植物生存工具包的替代剪切:在非生物应激反应中的分子机制和农业应用
Zhi-Yao Wang1,2, Wei Zhang3, Nai-Chao Zhang4
1State Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475004, China.
Journal of experimental botany
|February 6, 2026
概括
植物中的替代拼接 (AS) 通过改变基因活性来帮助它们在压力下生存. 操纵AS为全球粮食安全创造更坚固,更高产的作物提供了新的途径.
科学领域:
- 植物分子生物学 植物分子生物学
- 基因组学就是基因组学.
- 生物技术是生物技术.
背景情况:
- 替代拼接 (AS) 扩大了蛋白质组的多样性,对于植物适应环境压力至关重要.
- AS调节压力信号,转录网络和蛋白质功能,以实现最佳的植物健康.
- 最近的技术进步提高了我们对植物系统的理解.
研究的目的:
- 审查AS在植物应激反应中的分子机制.
- 探索AS工程在精密农业中的尖端应用.
- 突出AS操纵在作物改善方面的潜力.
主要方法:
- 关于植物替代拼接的最新文献的综述.
- 分析高通量测序数据 (长读转录组测序,单细胞RNA分析).
- 检查基因编辑技术 (CRISPR-Cas9) 和拼接因子 (SF) 工程.
主要成果:
- AS在调解植物对干旱,盐度和极端温度等非生物压力的反应中发挥着关键作用.
- 发现揭示了前所未有的分辨率的AS景观.
- 创新的AS工程策略正在出现用于作物增强.
结论:
- AS操纵是开发具有提高产量和营养价值的适应气候作物的关键.
- 精准农业可以利用AS工程来应对全球粮食安全挑战.
- 用生物技术工具合成基本的AS知识为农业提供了变革性的潜力.
相关概念视频
Alternative RNA Splicing
25.2K
Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity.
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
25.2K
Alternative RNA Splicing
5.2K
5.2K
Responses to Heat and Cold Stress
14.9K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
14.9K
Responses to Salt Stress
14.6K
Salt stress—which can be triggered by high salt concentrations in a plant’s environment—can significantly affect plant growth and crop production by influencing photosynthesis and the absorption of water and nutrients.
14.6K
Photoreceptors and Plant Responses to Light
28.5K
Light plays a significant role in regulating the growth and development of plants. In addition to providing energy for photosynthesis, light provides other important cues to regulate a range of developmental and physiological responses in plants.
28.5K
RNA Splicing
60.7K
Splicing is the process by which eukaryotic RNA is edited before its translation into protein. The RNA strand transcribed from eukaryotic DNA is called the primary transcript. The primary transcripts that become mRNAs are called precursor messenger RNAs (pre-mRNAs). Eukaryotic pre-mRNA contains alternating sequences of exons and introns. Exons are nucleotide sequences that code for proteins, whereas introns are the non-coding regions. In RNA splicing, introns are removed and exons are bonded...
60.7K


