对等离子激活凝的机械洞察:RONS运输,储存和杀菌协同作用
Jinkun Chen1, Weiji Yang1, Mingyan Zhang1
1State Key Laboratory of Electrical Insulation and Power Equipment, Centre For Plasma Biomedicine, Xi'an Jiaotong University, Xi'an, P. R. China.
Advanced healthcare materials
|February 6, 2026
概括
激活等离子体的水凝有效地储存反应性氧和物种 (RONS),以增强抗菌活性. 这项研究揭示了RONS在水凝中如何相互作用,提高了对抗药物耐药微生物的杀菌效果.
科学领域:
- 生物材料科学 生物材料科学
- 等离子体物理学的物理学
- 微生物学 微生物学
背景情况:
- 耐药微生物感染给全球健康带来了重大挑战.
- 冷大气压等离子体产生具有抗菌性能的反应性氧和物种 (RONS).
- 等离子激活凝 (PAHs) 为持续的RONS输送提供了一个有前途的平台.
研究的目的:
- 研究RONS加载,储存和水凝内部相互作用的机制.
- 为RONS透建立一个扩散反应模型.
- 了解RONS和释放的离子对增强抗菌活性的协同作用.
主要方法:
- 开发一个扩散反应模型来描述RONS在水凝中的运输.
- 在PAH中使用真空冷干燥用于RONS的纳入和储存.
- 调查RONS诱导的离子释放 (NH4+) 以及它对杀菌功效的影响.
主要成果:
- RONS加载涉及界面溶解和矩阵透,由扩散和反应控制.
- 在真空冷干燥的PAH有效地储存RONS,在再水时再生它们.
- RONS和NH4+之间的协同作用显著提高了PAHs的杀菌效果.
结论:
- 阐明RONS装载和储存在水凝中的基本机制.
- 通过RONS和离子协同作用来证明增强的抗菌活性.
- 为设计先进的等离子体激活抗菌材料提供了一种机械基础.
相关概念视频
01:55Secondary Active Transport
138.0K
One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme “pump” embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...
138.0K
01:32Secondary Active Transport
9.7K
One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme "pump" embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...
9.7K
01:47Primary Active Transport
199.4K
In contrast to passive transport, active transport involves a substance being moved through membranes in a direction against its concentration or electrochemical gradient. There are two types of active transport: primary active transport and secondary active transport. Primary active transport utilizes chemical energy from ATP to drive protein pumps that are embedded in the cell membrane. With energy from ATP, the pumps transport ions against their electrochemical gradients—a direction...
199.4K
01:29Primary Active Transport
14.4K
In contrast to passive transport, active transport involves a substance being moved through membranes in a direction against its concentration or electrochemical gradient. There are two types of active transport: primary active transport and secondary active transport. Primary active transport utilizes chemical energy from ATP to drive protein pumps embedded in the cell membrane. With energy from ATP, the pumps transport ions against their electrochemical gradients—a direction they would...
14.4K
01:14Active Transport
2.2K
Active transport is a critical biological process that allows cells to move solutes against an electrochemical gradient. This process requires direct energy input and is characterized by its selectivity, saturability, and susceptibility to competitive inhibition.
Primary active transporters, like Na+, K+ and -ATPase, directly utilize ATP to move ions across the membrane. These transporters play significant roles in various physiological processes. For instance, Na+, K+ and -ATPase maintain...
Primary active transporters, like Na+, K+ and -ATPase, directly utilize ATP to move ions across the membrane. These transporters play significant roles in various physiological processes. For instance, Na+, K+ and -ATPase maintain...
2.2K
02:12Short-distance Transport of Resources
17.7K
Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
17.7K