怀孕期间母亲的营养不平衡以及胎儿心血管疾病的发展
Shihua Cui1,2,3, Fengying Deng2, Muxue Lu2
1School of Life Science and Technology, Shandong Second Medical University, Weifang, China.
Frontiers in nutrition
|February 6, 2026
概括
怀孕期间母亲的营养显著影响后代的心血管健康. 营养不平衡可能导致胎儿的适应,增加晚年心血管疾病 (CVD) 的风险.
科学领域:
- 发育生物学 发展生物学
- 营养科学 营养科学
- 心血管医学 心血管医学
背景情况:
- 产前期对胎儿心血管发育至关重要.
- 母亲的营养状况会影响后代的长期心血管健康.
- 怀孕期间的营养不平衡与后代心血管疾病 (CVD) 风险增加有关.
研究的目的:
- 审查母亲营养不平衡对后代心血管健康的影响.
- 讨论将产前营养与产后心血管疾病联系在一起的机制.
- 确定未来的研究和干预策略.
主要方法:
- 文献综述综合当前知识.
- 讨论流行病学证据和机制性见解.
- 专注于宏观营养素和微量营养素失衡,酒精和咖啡因暴露.
主要成果:
- 孕产妇营养不良,过度营养和特定营养素缺乏会对胎儿血管发育产生不利影响.
- 机制包括表观遗传调节,氧化应激和内皮功能障碍.
- 产前暴露会使后代更容易患上晚年心血管疾病.
结论:
- 优化孕产妇的营养是预防心血管疾病的关键公共卫生战略.
- 早期的营养干预可以减轻长期的心血管风险.
- 解决代际代谢疾病需要专注于产前营养.
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