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Updated: Feb 7, 2026

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患有早期结直肠癌的患者的生殖细胞基因组分析

G Mauri1, M Puzzono2, A Mannucci2

  • 1Department of Hematology, Oncology and Molecular Medicine, Grande Ospedale Metropolitano Niguarda, Milano, Italy.

ESMO gastrointestinal oncology
|February 6, 2026
PubMed
概括

大约五分之一的早期结直肠癌 (EO-CRC) 病例与遗传综合征有关. 在FLCN和SDHAF2中确定了生殖系致病变体,这表明当前的指导方针可能低估了它们在EO-CRC中的重要性.

关键词:
这是一个BRAFBRAF.在FLCN基因.在SDHAF2基因中,SDHAF2基因被发现.早期发作的结直肠癌.遗传学 遗传学 遗传学 是一个封印戒指细胞癌瘤是什么?

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